Beeswax was used as dental fillings in Neolithic times.
The discovery of a 6,500-year-old human mandible in Slovenia demonstrated evidence of prehistoric dentistry with its left crown showing traces of a beeswax filling.
Researchers reported that this was “likely aimed to relieve tooth sensitivity derived from either exposed dentine and/or the pain resulting from chewing on a cracked tooth: this would provide the earliest known direct evidence of therapeutic-palliative dental filling”.
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